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In infants and toddlers (N = 8) with infantile spasms, visual and somatosensory evoked
potentials (VEP, SEP) were recorded during the course of the illness. During hypsarrhythmia
the pattern evoked potential was missing (7/8) or grossly abnormal (1/8), indicating
functional amaurosis. Flash evoked responses were normal in 50% even during the EEG-status,
showing the superiority of pattern versus flash evoked potentials for visual functions
in infancy. The alterations were reversible after successful treatment. Early SEP-components
remained normal even during the bioelectrical status but later cortical components
were altered in a reversible manner. The results show the objective state of functional
sensory block during the EEG-status and underline the necessity of quick and effective
treatment to avoid delayed visual maturation.
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References
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© 1987 Published by Elsevier Inc.
