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Research Article| Volume 4, ISSUE 2, P127-136, 1982

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Developmental changes of brainstem auditory evoked potentials (BAEPs) in normal human subjects from infants to young adults

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      BAEP has been found to be useful for assessment of subcortical maturation. However, the precise maturational changes of the peripheral and central transmission in normal human subjects are still open to controversy. We obtained a total of 200 BAEPs from 165 normal human subjects ranging from infants to young adults. Electrodes were placed at both mastoids and the reference at the vertex. 85 dB SL click stimuli were presented binaurally at a rate of 13/sec and 2,048 responses were summated on line with an averager. Investigation of the maturation of the transmission time indicated that the peripheral auditory apparatus attains functional maturity during the first 2 months of life, whereas the central transmission time shortens up to the age of 5 to 8 years. III-II and V-IV interpeak latencies (IPLs) showed maturational changes similar to those of V-I IPLs, in contrast II-I and IV-III showed little changes. A clear increase of the amplitude of peak V up to 4 years of age and a subsequent decreasing tendency was observed. The V-I IPLs of males were longer than those of females in each age group. Females also displayed larger BAEPs for wave V than males after 2 years of age. These data indicate that it is worthwhile to have separate latency and amplitude norms for males and females from infants to adults for attaching diagnostic significance to BAEP measures.

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      References

        • Sohmer H
        • Feinmesser M
        Cochlear and cortical audiometry.
        Isr J Med Sci. 1970; 6: 219-223
        • Jewett DL
        • Romano MN
        • Williston JS
        Human auditory evoked potentials: possible brain stem components detected on the scalp.
        Science. 1970; 167: 1517-1518
        • Jewett DL
        • Romano MN
        Neonatal development of auditory system potentials averaged from the scalp of rat and cat.
        Brain Res. 1972; 36: 101-115
        • Lieberman A
        • Sohmer H
        Standard values of amplitude and latency of cochlear audiometry (electro-cochleography) responses in different age groups.
        Arch Otorhinolaryngol (Berl). 1973; 203: 267-273
        • Hecox K
        • Galambos R
        Brain stem auditory evoked responses in human infants and adults.
        Arch Otolaryngol. 1974; 99: 30-33
        • Salamy A
        • McKean CM
        Postnatal development of human brainstem potentials during the first year of life.
        Electroencephalogr Clin Neurophysiol. 1976; 40: 418-426
        • Galambos R
        • Hecox KE
        Clinical applications of the auditory brainstem response.
        Otolaryngol Clin North Am. 1978; 11: 709-722
        • Fabiani M
        • Sohmer H
        • Tait C
        • Gafni M
        • Kinarti R
        A functional measure of brain activity: brain stem transmission time.
        Electroencephalogr Clin Neurophysiol. 1979; 47: 483-491
        • Stockard JE
        • Stockard JJ
        • Westmoreland BF
        • Corfits JL
        Brain stem auditory evoked responses: normal variation as a function of stimulus and subject characteristics.
        Arch Neurol. 1979; 36: 823-831
        • Starr A
        • Hamilton AE
        Correlation between confirmed sites of neurological lesions and abnormalities of far-field auditory brainstem responses.
        Electroencephalogr Clin Neurophysiol. 1976; 41: 595-608
        • Achor LJ
        • Starr A
        Auditory brain stem responses in the cat. I. Intracranial and extracranial recordings.
        Electroencephalogr Clin Neurophysiol. 1980; 48: 154-173
        • Horiuchi K
        Auditory brain stem response and its clinical application (in Japanese).
        Nippon Jibiinkoka Gakkai Kaiho (Tokyo). 1975; 78: 807-819
        • Starr A
        • Amlie RN
        • Martin WH
        • Sanders S
        Development of auditory function in newborn infants revealed by auditory brainstem potentials.
        Pediatrics. 1977; 60: 831-839
        • Pratt H
        • Ben-David Y
        • Peled R
        • Podoshin L
        • Scharf B
        Auditory brain stem evoked potentials: Clinical promise of increasing stimulus rate.
        Electroencephalogr Clin Neurophysiol. 1981; 51: 80-90
        • Achor LJ
        • Starr A
        Auditory brain stem responses in the cat. II. Effects of lesions.
        Electroencephalogr Clin Neurophysiol. 1980; 48: 174-190
        • Stockard JJ
        • Stockard JE
        • Sharbrough FW
        Non-pathologic factors influencing brainstem auditory evoked potentials.
        Am J EEG Technol. 1978; 18: 177-209
        • Kaga K
        • Tanaka Y
        Auditory brainstem response and behavioral audiometry.
        Arch Otolaryngol. 1980; 106: 564-566
        • Straumanis Jr, JJ
        • Shagass C
        • Overton DA
        Auditory evoked responses in young adults with Down's syndrome and idiopathic mental retardation.
        Biol Psychiatry. 1973; 6: 75-79
        • McClelland RJ
        • McCrea RS
        Gender differences in the auditory evoked brainstem response.
        Electroencephalogr Clin Neurophysiol. 1977; 43: 578-579
        • Michalewski HJ
        • Thompson LW
        • Patterson JV
        • Bowman TE
        • Litzelman D
        Sex differences in the amplitudes and latencies of the human auditory brain stem potential.
        Electroencephalogr Clin Neurophysiol. 1980; 48: 351-356