Abstract
Background
Internal carotid artery (ICA) absence (agenesis or aplasia) is a rare congenital anomaly
that is usually asymptomatic and found coincidentally. There has been no report showing
a specific chromosomal abnormality causes ICA absence.
Case reports
MR angiography in a Japanese male infant with trisomy 18 revealed left ICA absence
with the left middle cerebral artery (MCA) and anterior cerebral artery (ACA) supplied
from the ipsilateral posterior communicating artery and anterior communicating artery
(ACoA), respectively, type A in Lie’s classification. Another Japanese male infant
with trisomy 18 showed right ICA absence with the right ACA and MCA supplied from
the ACoA, that is, type B in Lie’s classification.
Conclusion
There have been no pathological or radiological reports of ICA absence in trisomy
18, however, it may be underestimated because the anomaly usually causes no clinical
symptoms. It is necessary to evaluate further patients to clarify whether or not unilateral
ICA absence is a characteristic congenital malformation.
Keywords
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Article info
Publication history
Published online: January 08, 2022
Accepted:
December 22,
2021
Received in revised form:
December 22,
2021
Received:
September 11,
2021
Identification
Copyright
© 2021 The Japanese Society of Child Neurology Published by Elsevier B.V. All rights reserved.
