Abstract
Background
Neurological manifestations caused by hypoglycemia range from reversible focal deficits
and transient encephalopathy to irreversible coma or death. Recently, high signal
intensity lesions in the splenium of the corpus callosum on diffusion-weighted magnetic
resonance imaging were reported in adults experiencing hypoglycemia. However, patients
presenting with agraphia are rare.
Subject and methods
We examined a 17-year-old left-handed female patient with type 1 diabetes who exhibited
transient left agraphia with a reversible splenium lesion of the corpus callosum on
diffusion-weighted imaging caused by hypoglycemia, which was improved with blood glucose
management alone.
Conclusion
This rare case indicates that agraphia, a sign of callosal disconnection syndrome,
can result from a reversible splenial lesion of the corpus callosum caused by hypoglycemia.
Keywords
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Article info
Publication history
Published online: March 29, 2018
Accepted:
March 14,
2018
Received in revised form:
February 24,
2018
Received:
December 6,
2017
Identification
Copyright
© 2018 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.
