Abstract
Alice in Wonderland Syndrome was originally coined by Dr. John Todd in 1955. The syndrome
is named after the sensations experienced by the character Alice in Lewis Carroll’s
novel Alice’s Adventures in Wonderland. Alice in Wonderland Syndrome consists of metamorphopsia (seeing something in a distorted
fashion), bizarre distortions of their body image, and bizarre perceptual distortions
of form, size, movement or color. Additionally, patients with Alice in Wonderland
Syndrome can experience auditory hallucinations and changes in their perception of
time. Currently, there is no known specific cause of Alice in Wonderland Syndrome.
However, theories point to infections such as the Epstein–Barr virus, medications
such as topiramate and associated migraines. Neuroimaging studies have revealed brain
regions involved with the manifestation of symptoms. These include the temporo-parietal
junction within the temporal lobe and the visual pathway, specifically the occipital
lobe. There are no current treatments for Alice in Wonderland Syndrome. Further research
is needed to find better treatments for Alice in Wonderland Syndrome and to elucidate
the exact cause or causes of Alice in Wonderland Syndrome.
Keywords
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Article info
Publication history
Published online: February 08, 2017
Accepted:
January 10,
2017
Received in revised form:
January 9,
2017
Received:
July 2,
2015
Identification
Copyright
© 2017 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.
