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Laryngeal dystonia in xeroderma pigmentosum

  • Ayako Muto
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan

    Department of Pediatrics, Tokyo Women's Medical University, Tokyo, Japan
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  • Akira Matsui
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan
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  • Yoshiaki Saito
    Correspondence
    Corresponding author. Address: Department of Child Neurology, Faculty of Medicine, Institute of Neurological Sciences, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. Tel.: +81 45 352 6551; fax: +81 45 352 6553.
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan

    Department of Pediatrics, Tokyo Women's Medical University, Tokyo, Japan
    Search for articles by this author
  • Hiroko Iwamoto
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan
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  • Kaori Kaneko
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan

    Department of Pediatrics, Tokyo Women's Medical University, Tokyo, Japan
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  • Kaori Masuko
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan
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  • Yuri Chikumaru
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan
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  • Kazuyo Saito
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan
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  • Seiji Kimura
    Affiliations
    Department of Pediatrics and Pediatric Neurology, Yokohama Ryo-iku Medical Center, 557-2 Ichizawa-cho, Asahi-ku, Yokohama 241-0014, Japan
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      Abstract

      We report on three patients with xeroderma pigmentosum group A (XPA) who showed laryngeal stridor in their 20s. The stridor appeared on feeding and emotional excitation, was exaggerated during respiratory infection and was life-threatening on some occasions. Adduction of the vocal cords during inspiration, observed by laryngoscopy, confirmed laryngeal dystonia in all cases. This type of focal dystonia may be characteristic in XPA and requires special attention during the management of these patients to avoid serious complications.

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