Abstract
This study details a case of Rett Syndrome where the patient's respiratory dysfunction
was improved after buspirone was administered. Polygraphic studies in the waking state,
before and after treatment with 5 mg of buspirone twice a day, were obtained. Breathing movements, oxygen saturation
and end-tidal carbon were monitored. Average oxygen saturation increased from 86.9
to 91%, and the period of saturation below 90% was reduced by 42.2%. The oxygen saturation
improvement observed in this case suggests that buspirone might be useful in treating
respiratory dysfunction associated with Rett Syndrome. Controlled clinical trials
are needed to provide more evidence.
Keywords
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Article info
Publication history
Accepted:
September 18,
2004
Received in revised form:
August 16,
2004
Received:
September 16,
2003
Identification
Copyright
© 2004 Published by Elsevier Inc.
