Abstract
We report a 3-year-old patient who presented a secondary acute neurological deterioration
clinically characterized by a partial Kluver–Bucy syndrome, 1 month after the onset
of herpes simplex encephalitis. This episode is unlikely due to continuation or resumption
of cerebral viral replication but might be related to an immune-inflammatory process.
In children, postinfectious immune-mediated encephalitis occuring after HSE are usually
clinically characterized by choreoathetoid movements. This type of movement disorder
was, however, not observed in this patient. On the basis of this case and a review
of the literature, we hypothesize the existence of a spectrum of secondary immune-mediated
process triggered by herpes simplex virus cerebral infection ranging from asymptomatic
cases with diffuse white matter involvement to secondary acute neurological deteriorations
with or without extrapyramidal features.
Keywords
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Article info
Publication history
Accepted:
July 22,
2004
Received in revised form:
June 9,
2004
Received:
January 20,
2004
Identification
Copyright
© 2004 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
