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Case report| Volume 27, ISSUE 1, P70-72, January 2005

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Pathological study of bronchospasms/tracheomalasia in patients with severe motor and intellectual disabilities

  • Eiko Ohtsuka
    Correspondence
    Corresponding author. Address: Department of Pediatrics, Metropolitan Fuchu Medical Center for Severe Motor and Intellectual Disabilities, 2-9-2, Musashidai, Fuchu-shi, Tokyo 183-0042, Japan. Tel.: +81-42-323-5115; fax: +81-42-322-6207
    Affiliations
    Department of Pediatrics, Metropolitan Fuchu Medical Center for Severe Motor and Intellectual Disabilities, 2-9-2, Musashidai, Fuchu-shi, Tokyo 183-0042, Japan

    Department of Pediatrics, Tokyo Women's Medical University, Tokyo, Japan
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  • Masaharu Hayashi
    Affiliations
    Department of Clinical Neuropathology, Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan
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  • Kimiko Hamano
    Affiliations
    Department of Pediatrics, Metropolitan Fuchu Medical Center for Severe Motor and Intellectual Disabilities, 2-9-2, Musashidai, Fuchu-shi, Tokyo 183-0042, Japan
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  • Satoko Kumada
    Affiliations
    Department of Pediatrics, Metropolitan Fuchu Medical Center for Severe Motor and Intellectual Disabilities, 2-9-2, Musashidai, Fuchu-shi, Tokyo 183-0042, Japan
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  • Akira Uchiyama
    Affiliations
    Department of Pediatrics, Metropolitan Fuchu Medical Center for Severe Motor and Intellectual Disabilities, 2-9-2, Musashidai, Fuchu-shi, Tokyo 183-0042, Japan
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  • Kiyoko Kurata
    Affiliations
    Department of Pediatrics, Metropolitan Fuchu Medical Center for Severe Motor and Intellectual Disabilities, 2-9-2, Musashidai, Fuchu-shi, Tokyo 183-0042, Japan
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  • Makiko Osawa
    Affiliations
    Department of Pediatrics, Tokyo Women's Medical University, Tokyo, Japan
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      Abstract

      This report concerns two autopsy cases of severe motor and intellectual disabilities (SMID) who died of bronchospasms or tracheomalasia. One case had no anatomical change in the tracheal wall except for an endotracheal granuloma, while the other showed softening of the tracheal wall. Since patients with SMID have risk factors for bronchospasms and tracheomalasia, such as gastro-esophageal reflux, aspiration, and thoracic deformities, it is important that we suspect the possibility of these conditions, when we see the respiratory distress in cases of SMID.

      Keywords

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