Abstract
We describe the long-term follow-up of a patient with bilateral striatal necrosis
associated with Mycoplasma pneumoniae infection occurred in adolescence. In the literature there are no longitudinal studies
of such a rare condition. Our patient, 4 years after the onset of an acute and reversible
akinetic-rigid syndrome, showed a severe obsessive-compulsive disorder, cognitive
decline, and a neuropsychological profile characterized by signs of deficient executive
functioning. The clinical picture that emerged in our patient is suggestive of a frontosubcortical
dementia which might be considered a major long-term sequela of the bilateral selective
striatal necrosis and consequent dysfunction of frontostriatal connections.
Keywords
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References
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Article info
Publication history
Accepted:
March 16,
2004
Received in revised form:
March 11,
2004
Received:
December 30,
2003
Identification
Copyright
© 2004 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
