Abstract
The authors report a 4-year-old girl who developed brain stem glioblastoma. Meningeal
irritation was present at onset. Magnetic resonance imaging revealed intracranial
and intraspinal leptomeningeal dissemination, which progressed faster than the original
tumor. Multiple large cysts developed at the interhemispheric and prepontine cisterns,
resulting in progressive obstructive hydrocephalus. The patient survived only 5 months
after presentation. Histology was verified by autopsy.
Keywords
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References
- Pattern of recurrence in brain stem gliomas: evidence for craniospinal dissemination.Int J Radiat Oncol Bio Phys. 1998; 40: 677-680
- Pediatric brain stem gliomas: an update.Child's Nerve Syst. 1998; 14: 167-173
- Treatment of Children with newly diagnosed brain stem gliomas with intravenous recombinant β-interferon and hyperfractionated radiation therapy.Cancer. 1996; 77: 2150-2156
- Chemotherapy for brain stem gliomas.Child's Nerve Syst. 1999; 15: 545-553
- Primitive neuroectodermal tumor of the brainstem: investigation of seven cases.Pediatrics. 2000; 106: 1045-1053
- Brainstem glioma: clinical manifestations of meningeal gliomatosis.Ann Neurol. 1983; 14: 177-182
- Brain stem and spinal metastasis of supratentorial glioblastoma multiforme: a clinical series.Neurosurgery. 1990; 27: 516-522
- Infratentorial glioblastoma: the role of neuraxis irradiation.Int J Radiat Oncol Bio Phys. 1982; 8: 999-1003
- Low-grade astrocytoma with neuraxis dissemination at diagnosis.J Neurosurg. 1995; 83: 67-71
- Hydrocephalus and intracranial tumor.J Neurosurg. 1981; 55: 174-182
Article info
Publication history
Accepted:
March 11,
2004
Received in revised form:
March 10,
2004
Received:
September 24,
2003
Identification
Copyright
© 2004 Published by Elsevier Inc.
