Abstract
To evaluate central nervous system functioning involvement in nocturnal enuresis,
P300 and N200 event-related brain potentials and brainstem auditory-evoked potentials
(BAER) were assessed in a group of 35 enuretic boys aged 7–9 years. The measurements
of enuretic group were compared to those of age and sex matched non-enuretics. P300
latency in the enuretic group was significantly longer than in non-enuretic group
(420 ms at parietal scalp (Pz), 414 ms at central scalp (Cz) versus 386 ms at Pz,
376 ms at Cz; P<0.01 and P<0.01, respectively). Both enuretic and non-enuretic subjects were divided into three
subgroups his age. There was no significant difference in terms of both P300 amplitude
and N200 latency and N200 amplitude between non-enuretic age subgroups. But, P300
latency over central scalp in 8 years old non-enuretic subgroup was significantly
longer than in 9 years old non-enuretic subgroup (P<0.01). No significant difference was found in latency and amplitude of P300 and N200
latency between enuretic subgroups. However, N200 amplitude at Cz in 8 years old enuretic
subgroup was significantly lower than both in 7 years old enuretic subgroup and in
9 years old enuretic subgroup (P<0.01 and P<0.01, respectively). There were significant topographical differences in latency
and amplitude of P300 and in N200 latency in enuretic age subgroups, only. There was
no significant difference in interpeak latencies I–III, I–V and III–V and wave latencies
I, III and V of BAERs between enuretic group and non-enuretic subgroup. Longer interpeak
and wave latencies of BAERs were found both in 8 years old enuretic subgroup and 8
years old non-enuretic subgroup.
Conclusion: Longer P300 latency in primer enuretics compare to non-enuretics is an
evidence of a maturational delay of central nervous system functioning.
Keywords
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Article info
Publication history
Accepted:
May 13,
2002
Received in revised form:
April 16,
2002
Received:
January 18,
2002
Footnotes
☆The study was presented at Seventh Child Neurology Congress of Meditterrenian Countries, 30 May–1 Jun, 2001, Istanbul, Turkey.
Identification
Copyright
© 2002 Elsevier Science B.V. Published by Elsevier Inc. All rights reserved.
