Abstract
The aim of this study is to determine the general condition of preterm infants with
severe brain lesions and to compare it with that of normal preterm infants. The Score
for Neonatal Acute Physiology (SNAP) was calculated in nine preterm infants with periventricular
leukomalacia (PVL) whose initial electroencephalograms showed grade IV depression
(PVL group), 18 preterm infants who did not require mechanical ventilation during
the neonatal period, Spontaneous respiration (SR group), and 18 preterm infants who
required mechanical ventilation (MV group). The sum of the following four items in
SNAP was separately calculated and called the ‘lung score’: PaO2, PaO2/FiO2 ratio, PaCO2, and oxygenation index. In addition to SNAP, we evaluated some neonatal variables.
SNAP is lower in the SR group than in the PVL (P<0.05) or MV (P<0.01) groups. The lung score was also lower in the SR group than in the PVL (P<0.05) or MV (P<0.01) groups. On the other hand, the residual score (SNAP minus lung score) was not
significantly different among the three groups. The physical condition of infants
with PVL was not poor, although respiratory distress was often observed.
Keywords
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Article info
Publication history
Accepted:
August 27,
2001
Received in revised form:
July 23,
2001
Received:
March 15,
2001
Identification
Copyright
© 2001 Elsevier Science B.V. Published by Elsevier Inc. All rights reserved.
