Original article| Volume 23, ISSUE 7, P580-583, November 2001

A population-based neuroepidemiological survey of West syndrome in Okayama Prefecture, Japan


      It is important for the fields of child neurology and child public health to clarify the prevalence and incidence rates of West syndrome because this syndrome is a major cause of developmental disorders.
      However, there have been few reports in Japan on the prevalence rate of West syndrome in the general population.
      We carried out a population-based survey in Okayama Prefecture, in western Japan in 1994. The population under 2 years of age in Okayama Prefecture in 1994 was 37,085. Six cases of West syndrome were identified. The prevalence rate was 0.16 per 1000.


      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Brain and Development
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Oka E
        • Murakami N
        • Sanada S
        • Asano T
        • Akiyama T
        Neuroepidemiological study of childhood epilepsy in Okayama Prefecture; West syndrome and severe myoclonic epilepsy in infancy.
        (in Japanese)in: Kondo K 1994–1996 Annual Report of Research Group for Frequency, Risk Factor and Prevention of Mental and Muscular Diseases. 1997: 54-59 (sponsored by the National Center of Neurology and Psychiatry, the Ministry of Health and Welfare, Japan, Tokyo)
        • Ishida S
        Prevalence of epilepsy in Okayama Prefecture; A neuroepidemiologic study.
        Folia Psychiatr Neurol Jpn. 1985; 39: 325-332
        • Tsuboi T
        Prevalence and incidence of epilepsy in Tokyo.
        Epilepsia. 1988; 29: 103-110
        • Matsuo A
        • Matsusaka T
        • Tsuru A
        • Moriuchi H
        • Nakashita Y
        • Tanaka S
        • et al.
        Epidemiological and clinical study of West syndrome in Nagasaki Prefecture, Japan.
        No To Hattatsu (Tokyo). 2001; 33 (in Japanese): 15-20
        • Riikonen R
        • Donner M
        Incidence and aetiology of infantile spasms from 1960 to 1976: a population study in Finland.
        Dev Med Child Neurol. 1979; 21: 333-343
        • Hauser W.A
        • Annegers J.F
        • Gomez M.R
        Incidence of West syndrome.
        Epilepsia. 1991; 32: 83
        • Ludvigsson P
        • Olafsson E
        • Sigurdardottir S
        • Hauser W.A
        Epidemiologic features of infantile spasms in Iceland.
        Epilepsia. 1994; 35: 802-805
        • Sidenvall R
        • Eeg-Olofsson O
        Epidemiology of infantile spasms in Sweden.
        Epilepsia. 1995; 36: 572-574
        • Trevathan E
        • Murphy C.C
        • Yeargin-Allsopp M
        The descriptive epidemiology of infantile spasms among Atlanta children.
        Epilepsia. 1999; 40: 748-751
        • Joensen P
        Prevalence, incidence, and classification of epilepsy in the Faroes.
        Acta Neurol Scand. 1986; 74: 150-155
        • Wendt L.V
        • Rantakallio P
        • Saukkonen A.L
        • Maekinen H
        Epilepsy and associated handicaps in a 1 year birth cohort in Northern Finland.
        Eur J Pediatr. 1985; 144: 149-151
        • Doose H
        • Sitepu B
        Childhood epilepsy in a German city.
        Neuropediatrics. 1983; 14: 220-224
        • Cowan L.D
        • Bodensteiner J.B
        • Leviton A
        • Doherty L
        Prevalence of the epilepsies in children and adolescents.
        Epilepsia. 1989; 30: 94-106
        • Bobo J.K
        • Thapa P.B
        • Anderson J.R
        • Gale J.L
        Acute encephalopathy and seizure rates in children under age two years in Oregon and Washington State.
        Am J Epidemiol. 1994; 140: 27-38
        • Okumura A
        • Hayakawa F
        • Kuno K
        • Watanabe K
        Periventricular leukomalacia and West syndrome.
        Dev Med Child Neurol. 1996; 38: 13-18