Abstract
Early-onset benign childhood occipital seizure susceptibility syndrome (EBOSS) recently
described by Panayiotopoulos, is an early-onset variant of benign childhood epilepsy
with occipital paroxysms. EBOSS is characterized by partial seizures that are predominantly
manifested at night and associated with deviation of the eyes, vomiting and impairment
of consciousness, but without ictal visual symptoms or postictal headache. The clinical
features of our case were consistent with those of EBOSS, and we therefore diagnosed
the patient as having a typical form of EBOSS. Neuroimaging by CT, MRI and MR angiography
did not reveal a focal lesion. Interictal single photon emission computed tomography
(SPECT) revealed decreased cerebral blood flow in the right occipital region corresponding
to the epileptogenic focus shown on EEG. It remains unclear whether our finding on
SPECT reflects secondary hypoperfusion due to minor morphological abnormality or immediate
functional hypoperfusion. No reference to SPECT in a case of EBOSS has appeared in
the literature to date. This report provides a better understanding of benign childhood
epileptic syndromes with occipital spikes.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Brain and DevelopmentAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Benign epilepsy of childhood with occipital paroxysms.in: Roger J. Epileptic syndrome in infancy, childhood and adolescence. John Libbey Eurotext, London1985: 159-170
- Proposal for classification of epilepsies and epileptic syndromes.Epilepsia. 1985; 26: 268-278
- Early-onset benign occipital seizure susceptibility syndrome.Epilepsia. 1997; 38: 285-293
- Early-onset benign childhood occipital seizure susceptibility syndrome: a syndrome to recognize.Epilepsia. 1999; 40: 621-630
- Cortical dysplasia in temporal lobe epilepsy: magnetic resonance imaging correlations.Ann Neurol. 1991; 29: 293-298
- Optimizing the diagnosis of hippocampal sclerosis using MR imaging.Am J Neuroradiol. 1993; 14: 753-762
- Ictal single photon emission computed tomography in occipital lobe seizures.Epilepsia. 1997; 38: 839-843
- Temporomesial epileptogenic focus in benign epilepsy of childhood with occipital paroxysms (BEOP).Neurocase. 1998; 4: 167-171
Article info
Publication history
Accepted:
July 30,
2001
Received in revised form:
July 28,
2001
Received:
March 15,
2001
Identification
Copyright
© 2001 Elsevier Science B.V. Published by Elsevier Inc. All rights reserved.
