Abstract
In a patient with holoprosencephaly, partial seizures had various initial ictal symptoms,
and ictal EEGs showed epileptogenic foci in the right and left brain. Partial seizures
did not culminate in secondary generalized tonic–clonic convulsions. Characteristic
malformed structures contribute to the absence of secondary generalization and the
presence of Jacksonian-type propagation.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Brain and DevelopmentAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Arhinencephalie als typische Art von Missbildung. Graz von Leuschner and Lubensky.Wien Med Bl. 1882; 5: 1395
- EEG in holoprosencephaly (arhinencephaly).Arch Neurol. 1964; 11: 507-520
- Mutations in the human sonic hedgehog gene cause holoprosencephaly.Nat Genet. 1996; 14: 357-360
- Holoprosencephaly.J Kanazawa Med Univ. 1978; 3: 117-125
- Two cases of holoprosencephaly.Shounika Shinryou. 1970; 33: 1507-1513
- Surgery for intractable infantile spasms: neuroimaging perspectives.Epilepsia. 1993; 34: 764-771
- Spread of the epileptic discharge; an experimental study of the after-discharge induced by electrical stimulation of the cerebral cortex.Arch Neurol Psychiatry. 1940; 43: 429-452
- Propagation of epileptic discharge from chronic neocortical foci in monkey.Epilepsia. 1965; 6: 297-309
- Periodic spasms: a particular type of infantile spasms.N Trends Pediatr Epileptol. 1991; : 111-118
- Partial seizures evolving to infantile spasms.Epilepsia. 1988; 29: 34-40
Article info
Publication history
Accepted:
April 9,
2001
Received in revised form:
April 3,
2001
Received:
March 21,
2000
Identification
Copyright
© 2001 Elsevier Science B.V. Published by Elsevier Inc. All rights reserved.