Abstract
We describe a series of 13 patients, ten males and three females, with ages ranging
between three and fourteen years, who show unilateral polymicrogyria (in the left
cerebral hemisphere in four cases and in the right in nine). The first and the main
clinical alteration in all 13 cases was hemiparesis that did not change along the
years. Ten patients had seizures that were completely controlled in seven. Three cases
never presented seizures. Spontaneous threat of abortion or arterial hypertension
during the first five months of pregnancy occurred in five cases. Weight less than
3 kg at birth was observed in six cases. The only patient who shows severe mental
retardation associated with deafness is a girl who had infantile spasms at 20 days
of age and presents duplication of a short arm of the chromosome X. Conventional magnetic
resonance (MR) studies, performed in four cases did not disclose polymicrogyria but
only an enlarged cortex that was diagnosed as cortical dysplasia. Three-dimensional
MR (3DMR) images are very important not only to see the polymicrogyria, but also its
extension and severity, especially if, moreover the axial, coronal and sagittal views,
oblique, frontal, occipital, basal and superior images of the hemispheric cortical
surface are performed.
Keywords
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Article info
Publication history
Accepted:
March 23,
2001
Received in revised form:
March 15,
2001
Received:
January 18,
2001
Identification
Copyright
© 2001 Elsevier Science B.V. Published by Elsevier Inc. All rights reserved.
