Abstract
A patient with acute necrotizing encephalophathy (ANE) following varicella infection
with a good prognosis is reported. A somatosensory evoked magnetic field (SEF) study
using a 37-channel-magnetoencephalography system demonstrated normal latency and strength
of the first component (N20m) elicited by median nerve stimulation, despite bilateral
symmetrical thalamic lesions on MRI. The normal SEF findings and the good prognosis
suggested a reversible breakdown of the blood–brain barrier, and an edematous process
as the brain pathology. Furthermore, our results support the idea of distinct generators
for the three earliest cortical SEF components (N20m, P30m, N45m).
Keywords
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Article info
Publication history
Accepted:
December 6,
2000
Received in revised form:
November 22,
2000
Received:
February 28,
2000
Identification
Copyright
© 2001 Elsevier Science B.V. Published by Elsevier Inc. All rights reserved.
