Advertisement
Research Article| Volume 16, ISSUE 1, P16-22, January 1994

Download started.

Ok

Acute hemiplegia syndrome in childhood

      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Three types of clinical features at the onset are well known to be characteristic of acute hemiplegia syndrome (AHS). Type 1 comprises status epilepticus of hemiconvulsions with fever. Representative diseases of this type are the infectious diseases of the central nervous system, acute encephalopathy and cerebral vascular diseases. Type 2 comprises status epilepticus of hemiconvulsions without fever. Cerebral vascular diseases and epilepsy are the major ones of this type. Type 3 comprises hemiplegia or hemiparesis of sudden onset without fever or convulsions. Most patients with this type had cerebral vascular diseases, about half of which were moyamoya disease in Japan. Recent progress in neuroimaging studies has allowed considerable elucidation of the etiology of AHS. Gadolinium-enhanced MRI showed minimal lesions such as capsular infarction more clearly than plain MRI. Acetazolamide test99mTc-HMPAO SPECT imaging is one of the useful assisted diagnostic techniques for moyamoya disease, because it reveals the reserve capacity of the collaterals. [123I]IMP SPECT is useful for the diagnosis and follow-up of acute disseminated encephalomyelitis (ADEM), as the images of the lesions coincide well with the MRI ones.99mTc-HMPAO SPECT in a case with alternating hemiplegia revealed normoperfusion in the ictal periods. Four cases of AHS are reported here.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Brain and Development
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Bickerstaff E.R.
        Aetiology of acute hemiplegia in childhood.
        Br Med J. 1964; 2: 82-87
        • Carter S
        • Gold A.P.
        Acute infantile hemiplegia.
        Pediatr Clin North Am. 1967; 14: 851-864
        • Solomon G.E.
        • Hilal S.K.
        • Gold A.P.
        • et al.
        Natural history of acute hemiplegia of childhood.
        Brain. 1970; 93: 107-120
        • Isler W
        Acute hemiplegias and hemisyndromes in childhood.
        Spastics International Medical Publications, London1971
        • Gold A.P.
        • Carter S
        Acute hemiplegia of infancy and childhood.
        Pediatr Clin North Am. 1976; 23: 413-433
        • Shirasaka Y
        • Ito M
        • Okuno T
        • Fujii T
        • Mikawa H
        Sequential [123I]IMP-SPECT in acute infantile hemiplegia.
        Peditr Neurol. 1989; 5: 306-310
        • Gastaut H
        • Pinsard N
        • Gastaut J.L.
        • Regis H
        • Michel B
        Acute hemiplegia in children.
        Adv Neurol. 1979; 25: 329-337
        • Kataoka H
        • Okuno T
        • Mikawa H
        • Hojo H
        Cranial computed tomographic and electroencephalographic abnormalities in children with post-hemiconvulsive hemiplegia.
        Eur Neurol. 1988; 28: 279-284
        • Verret S
        • Steele J.C.
        Alternating hemiplegia in childhood: a report of eight patients with complicated migraine beginning in infancy.
        Pediatrics. 1971; 47: 675-680
        • Krägeloh I
        • Aicardi J
        Alternating hemiplegia in infants: Report of five cases.
        Dev Med Child Neurol. 1980; 22: 784-791
        • Hosking G.P.
        • Cavanagh N.P.C.
        • Wilson J
        Alternating hemiplegia: complicated migraine of infancy.
        Arch Dis Child. 1978; 53: 656-659
        • Dittrich J
        • Havlova M
        • Nevsimalova S
        Paroxysmal hemiparesis in childhood.
        Dev Med Child Neurol. 1979; 21: 800-807
        • Okuno T
        • Takao T
        • Itoh M
        • Konishi Y
        • Nakano S
        • Mikawa H
        Acute hemiplegia in childhood.
        CT Kenkyu (Tokyo). 1983; 5 (in Japanese): 223-230
        • Okuno T
        • Takao T
        • Ito M
        • Konishi Y
        • Mikawa H
        • Nakano Y
        Infarction of the internal capsule in children.
        J Comput Assist Tomogr. 1980; 4: 770-774
        • Regli L
        • Regli F
        • Maeder P
        • Bogousslavsky J
        Magnetic resonance imaging with gadolinium contrast agent in small deep (lacunar) cerebral infarcts.
        Arch Neurol. 1993; 50: 175-180
        • Vorstrup S
        • Brun B
        • Lassen N.A.
        Evaluation of the cerebral vasodilatory capacity by the acetazolamide test before EC-IC bypass surgery in patients with occlusion of the internal carotid artery.
        Stroke. 1986; 17: 1291-1298
        • Matsuda H
        • Higashi S
        • Asli I.N.
        • Eftekhari M
        • Esmaili J
        • Seki H
        • et al.
        Evaluation of cerebral collateral circulationby Technetium-99m HM-PAO brain SPECT during the Matas test: Report of three cases.
        J Nucl Med. 1988; 29: 1724-1729
        • Okuno T
        • Takao T
        • Ito M
        • Mikawa H
        • Nakano Y
        Contrast enhanced hypodense areas in a case of acute disseminated encephalitis following influenza A virus.
        Computerized Radiol. 1982; 6: 215-217
        • Okuno T
        • Fuseya Y
        • Ito M
        • Konishi Y
        • Nakano Y
        Reversible multiple hypodense areas in the white matter diagnosed as acute disseminated encephalomyelitis.
        J Comput Assist Tomogr. 1981; 5: 119-121
        • Lukes S.A.
        • Norman D
        Computed tomography in acute disseminated encephalomyelitis.
        Ann Neurol. 1983; 13: 567-572
        • Ormerod I
        • Bronstein A
        • Rudge P
        • Johnson G
        • Macmanus D
        • Halliday A.M.
        • et al.
        Magnetic resonance imaging in clinically isolated lesions of the brain stem.
        J Neurol Neurosurg Psychiatr. 1986; 49: 737-743
        • Atlas S.W.
        • Grossman R.I.
        • Goldberg H.I.
        • Hackney D.B.
        • Bilaniuk L.T.
        • Zimmerman R.A.
        MR diagnosis of acute disseminated encephalomyelitis.
        J Comput Assist Tomogr. 1986; 10: 798-801
        • Kesselring J
        • Miller D.H.
        • Robb S.A.
        • Kendall B.E.
        • Moseley I.F.
        • Kingsley D
        • et al.
        Acute disseminated encephalomyelitis: MRI findings and the distinction from multiple sclerosis.
        Brain. 1990; 113: 291-302
        • Shirasaka Y
        • Ito M
        • Okuno T
        • Mikawa H
        • Yamori Y
        Epileptic seizures difficult to differentiate from alternating hemiplegia in infants: A case report.
        Brain Dev (Tokyo). 1990; 12: 521-524
        • Kanazawa O
        • Shirasaka Y
        • Hattori H
        • Okuno T
        • Mikawa H
        Ictal99mTc-HMPAO SPECT in alternating hemiplegia.
        Pediatr Neurol. 1991; 7: 121-124
        • Schlake H.P.
        • Bottger I.G.
        • Grotemeyer K.H.
        • Husstedt I.W.
        • Vollet B
        • Schober O
        • et al.
        Single photon emission computed tomography with technetium-99m hexamethyl propylenamino oxime in the pain-free interval of migraine and cluster headache.
        Eur Neurol. 1990; 30: 153-156
        • Nakamura Y
        • Nagano T
        • Mizuguchi M
        • Mizuno Y
        • Tamagawa K
        • Komiya K
        • et al.
        Alternating hemiplegia in infants: a case report.
        No To Hattatsu (Tokyo). 1986; 18 (in Japanese): 406-412
        • Sakuragawa N
        • Matsuo T
        • Kihira S
        • Matsuzaka T
        • Matsui A
        • Arima M
        • et al.
        Alternating hemiplegia in infancy: two case reports and reduced regional cerebral blood flow on 11CO2 dynamic positron emission tomography.
        Brain Dev (Tokyo). 1985; 7: 207
        • Sakuragawa N
        • Arima M
        • Matsumoto S
        Nationwide investigation of actual conditions of alternating hemiplegia of children in Japan.
        Nippon Shonika Gakkai Zasshi (Tokyo). 1988; 92 (in Japanese): 892-898
        • Hattori H
        • Hashizuka S
        • Matsuoka O
        • Murata R
        • Ueda T
        Alternating hemiplegia in infants: a case report with abnormal findings on ABR (auditory brain stem response) and SPECT (single photon emission CT).
        Shonika Rinsho (Tokyo). 1989; 42 (in Japanese): 77-82
        • Hanson P.A.
        • Chodos R
        Hemiparetic seizures.
        Neurology. 1978; 28: 920-923
        • Bonte F.J.
        • Stokely E.M.
        • Devons M.D.
        • Horman R.W.
        Single photon tomographic study of regional cerebral blood flow in epilepsy.
        Acta Neurol. 1983; 40: 267-270
        • Dietrich M.E.
        • Bergen D
        • Smith M.C.
        • Fariello R
        • Ali M
        Correlation of abnormalities of interictal n-isopropyl-p-iodoamphetamine single-photon emission tomography with focus of seizure onset in complex partial seizure disorders.
        Epilepsia. 1991; 32: 187-194
        • Ryding E
        • Rosen I
        • Elmqvist D
        • Ingvar D.H.
        SPECT measurements with99mTc-HMPAO in focal epilepsy.
        J Cereb Blood Flow Metab. 1988; 8: S95-S100
        • Stefan H
        • Bauer J
        • Feistel H
        • Schulemann H
        • Neubauer U
        • Wenzel B
        • et al.
        Regional cerebral blood flow during focal seizures of temporal and frontocentral onset.
        Ann Neurol. 1990; 27: 162-166