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Abstract
Two patients born to mothers who abused cocaine during pregnancy were found to have
various brain malformations, some of which were not previously reported. Children
who were exposed to cocaine or polysubstances prenatally and who present with a neurologic
deficit require neuroimaging studies to detect abnormalities.
Keywords
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Reference
- Effect of cocaine use on the fetus.N Engl J Med. 1992; 327: 399-407
- Teratogenicity of cocaine in humans.J Pediatr. 1987; 110: 93-96
- Perinatal cerebral infarction in maternal cocaine use.J Pediatr. 1986; 108: 456-459
- Brain and ocular abnormalities in infants with in utero exposure to cocaine and other street drugs.Am J Dis Child. 1992; 145: 688-695
- Maternal cocaine abuse: the spectrum of radiologic abnormalities in the neonatal CNS.AJNR. 1991; 12: 951-956
- Fetal akinesia deformation sequence (Pena-Shokeir phenotype) associated with acquired intrauterine brain damage.Neurology. 1991; 41: 1467-1468
- Effects of opiates on neuronal development in the rat cerebral cortex.Brain Res Bull. 1993; 30: 523-527
- Early neurogenesis and teratogenesis in whole mouse embryo cultures. Histochemical, immunocytological and ultrastructural study of the premigratory neuronal-glial units in normal mouse embryo and in mouse embryos influenced by cocaine and retinoic acid.J Neuropathol Exp Neurol. 1992; 51: 206-219
- Echoencephalographic findings in neonates associated with maternal cocaine and methamphetamine use: incidence and clinical correlates.J Pediatr. 1989; 115: 770-778
- Malformations of the central nervous system.in: Menkes JH Textbook of child neurology. Lea & Febiger, Philadelphia1985: 220-224
- Agenesis of corpus callosum.Am J Dis Child. 1985; 139: 953-955
- Schizencephalies. A study of the congenital clefts in the cerebral mantle. 1. Clefts with fused lips.J Neuropathol Exp Neurol. 1946; 5: 116-130
- Schizencephaly: correlation of clinical findings with MR characteristics.AJNR. 1992; 13: 85-94
- Prenatal cocaine exposure and fetal vascular disruption.Pediatrics. 1990; 85: 743-747
- Friede RL Developmental neuropathology. Springer, New York1989: 28-43
Article info
Publication history
Accepted:
February 4,
1994
Received:
November 1,
1993
Identification
Copyright
© 1994 Elsevier Science B.V. All rights reserved. Published by Elsevier Inc.