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The neuropathological study of an infant with severe perinatal asphyxia showed specific neuronal loss in the medial part of the inferior olivary nucleus and the lateral part of the cerebellar hemisphere. This distribution suggests that the partial loss of olivary neurons is due to trans-synaptic degeneration from contralateral cerebellar hemispheric lesions, immunohistochemistrically demonstrated by axonal loss and swelling of neurofilaments.
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Accepted: December 5, 1993
Received: March 19, 1993
© 1994 Elsevier Science B.V. All rights reserved. Published by Elsevier Inc.