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Abstract
Seventy-two children with Guillain-Barrésyndrome (GBS), diagnosed at 11 major teaching
hospitals in Taiwan during the period 1986–1990, were studied retrospectively. There
were 44 males and 28 females ranging in age from 7 months to 15 years. Preceding events
could be traced in 61 patients (85%), including antecedent infection in 59 patients
and previous vaccination in 2. As well as the consistent pictures of progressive weakness
and generalized hyporeflexia, there were sensory complaints (26%), cranial nerve lesions
(46%), respiratory failure (14%) and autonomic dysfunction (25%). Motor symptoms reached
a maximum within 20 days in 88% of the patients, with the plateau lasting less than
2 weeks in 75%, and became stable within 3 months in 76%. Overall outcome showed complete
recovery in 73% of the patients within 6 months after onset. Four (5.6%) had recurrence,
and there was no mortality. The present study revealed that the annual incidence of
GBS in Taiwan can be estimated roughly as 0.66 per 100, 000 and that the course of
childhood GBS is relatively benign.
Keywords
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Reference
- Polyneuropathy in childhood.Pediatrics. 1979; 64: 96-105
- Demyelination induced by serum from patients with Guillain-Barrésyndrome.Ann Neurol. 1984; 15: 163-170
- The role of autoantibody and immune complexes in the pathogenesis of the Guillain-Barrésyndrome.Ann Neurol. 1981; 9 (suppl): 70-79
- Immunological parameters in Guillain-Barrésyndrome.Ann Neurol. 1990; 27 (suppl): S25-S29
- Guillain-Barrédisease complex. A statement of diagnostic criteria and analysis of 100 cases.Arch Neurol. 1966; 14: 196-201
- The natural history of the Guillain-Barrésyndrome in 18 children and 50 adults.J Neurol Neurosurg Psychiatry. 1989; 52: 853-856
- Epidemiology of Guillain-Barrésyndrome.Neurology. 1978; 28: 686-690
- The epidemiology of Guillain-Barrésyndrome.Ann Neurol. 1990; 27 (suppl): S7-S12
- Guillain-Barrésyndrome: clinicoepidemiologic features and effect of influenza vaccine.Arch Neurol. 1985; 42: 1053-1057
- The Guillain-Barrésyndrome in childhood.Clin Pediatr (Phila). 1967; 6: 162-170
- The child neurological society in Taiwan: its history and present status.Brain Dev (Tokyo). 1987; 9: 65-66
- Criteria for diagnosis of Guillain-Barrésyndrome.Ann Neurol. 1978; 3: 565-566
- Assessment of current diagnostic criteria for Guillain-Barrésyndrome.Ann Neurol. 1990; 27 (suppl): S21-S24
- Five cases of acute infective polyneuritis (Guillain-Barrésyndrome) in children.Arch Dis Child. 1954; 29: 531-536
- Guillain-Barrésyndrome: another cause of the “floppy infant”.Am J Dis Child. 1977; 131: 699-700
- Guillain-Barrésyndrome in children.Pediatr Rev. 1986; 8: 69-74
- Guillain-Barrésyndrome: a 42-year epidemiologic and clinical study.in: 2nd ed. Mayo Clin Proc. 53. 1978: 118-122
- Epidemiology of the Guillain-Barrésyndrome in the county of Hordaland, Western Norway.Acta Neurol Scand. 1985; 71: 43-47
- Age-specific incidence of Guillain-Barrésyndrome in Oxfordshire.Quart J Med, New Series. 1990; 77: 1297-1304
- National surveillance for Guillain-Barrésyndrome: January 1978–March 1979.Neurology. 1983; 33: 150-157
- Guillain-Barrésyndrome in the United States, 1978–1981: additional observations from the national surveillance system.Neurology. 1983; 33: 633-637
- Guillain-Barrésyndrome with hydrocephalus in early infancy.Arch Neurol. 1977; 34: 567-569
- Neonatal Guillain-Barrésyndrome.Pediatr Neurol. 1988; 4: 255-256
- Acute polyradiculitis (Guillain-Barrésyndrome): an epidemiological study of 156 cases observed in Beijing.Ann Neurol. 1981; 9 (suppl): 146-148
- Pain in Guillain-Barrésyndrome.Arch Neurol. 1984; 41: 511-514
- Childhood Guillain-Barrésyndrome masquerading as a protracted pain syndrome.Arch Neurol. 1985; 42 (letter): 839
- Experiences with Guillain-Barrésyndrome in a pediatric intensive care unit.Intensive Care Med. 1987; 13: 328-331
- Prognosis in severe Guillain-Barrésyndrome.Arch Dis Child. 1987; 62: 288-291
- Immunoglobulins in serum and cerebrospinal fluid from patients with acute Guillain-Barrésyndrome.Acta Neurol Scand. 1986; 73: 388-393
- Effect of corticosteroids on the course of Guillain-Barrésyndrome.Lancet. 1974; i: 524-526
- The role of plasmapheresis in childhood Guillain-Barrésyndrome.Ann Neurol. 1990; 28: 65-69
- Plasmapheresis in children with Guillain-Barrésyndrome.Neurology. 1991; 41: 1928-1931
- Benefit of intravenously administrated immune serum globulin in patients with Guillain-Barrésyndrome.J Pediatr. 1990; 116: 141-144
Article info
Publication history
Accepted:
February 20,
1994
Received:
November 13,
1992
Identification
Copyright
© 1994 Elsevier Science B.V. All rights reserved. Published by Elsevier Inc.